JET-A Matlab Toolkit for Automated J-Difference-Edited MR Spectra Processing of In Vivo Mouse MEGA-PRESS Study at 9.4 T

Chen Liu, David Jing Ma, Nanyan Zhu, Kay Igwe, Jochen Weber, Roshell Li, Emily Turner Wood, Wafae Labriji, Vasile Stupar, Yanping Sun, Neil Harris, Antoine Depaulis, Florence Fauvelle, Scott A Small, Douglas L Rothman, Jia Guo
May, 2021
Cite ISMRM

Abstract

Spectral editing studies in mice brains have been limited due to difficulty in spectrum processing and lack of software package analysis. However, in preclinical studies, mouse models play an important role in understanding e ects of drugs and its impact on the nervous system. JET is a fully automated software that performs raw data conversion, spectrum registration, spectral quality assessment and metabolite quanti cation of MEGA-PRESS mouse data at 9.4 T. In this work, we rst introduce the automated spectra processing pipeline of JET and further demonstrate its utilities in mouse studies.

Type
Conference paper
Publication
In International Society for Magnetic Resonance in Medicine (ISMRM) 1-Page Abstract Oral Presentation
abstract
Chen Liu
Chen Liu
PhD Student in Computer Science

Researcher in machine learning and healthcare.